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NSC 102816
Descriptors Found:
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DeCS
Descriptor
English
:
Azacitidine
Descriptor
Spanish
:
Azacitidina
Descriptor
Portuguese
:
Azacitidina
Synonyms
English
:
5 Azacytidine
5-Azacytidine
Azacytidine
NSC 102816
NSC-102816
NSC102816
Vidaza
Tree Number:
D02.145.150
D03.383.742.680.245.217
D13.570.685.245.217
D13.570.800.286.300
Definition
English
:
A pyrimidine analogue that inhibits DNA methyltransferase, impairing
DNA methylation
. It is also an antimetabolite of
cytidine
, incorporated primarily into RNA. Azacytidine has been used as an antineoplastic agent.
Pharmacological Action:
Antimetabolites, Antineoplastic
Enzyme Inhibitors
History Note
English
:
96; was AZACYTIDINE 1972-95 (Prov 1972-73)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
1386
Unique Identifier:
D001374
Occurrence in VHL
:
Similar:
DeCS